Asuragen: Bio-Techne Launches New Panel Resolving Hard-To-Decipher Carrier Screening Genes

Bio-Techne Corporation announced that Asuragen, a Bio-Techne brand, has teamed up with Oxford Nanopore Technologies to launch the AmplideX®? Nanopore Carrier Plus Kit, a new genetic panel and supporting analysis software for carrier screening research. This innovative kit helps laboratories resolve genes that are challenging to analyze by conventional short-read sequencing and only partially resolved by ancillary assays. The panel is available for research use only. In 2021, the American College of Medical Genetics and Genomics (ACMG) updated its recommendations for carrier screening to include many genes that cannot be analyzed by standard short-read sequencing. In fact, half of the 10 most common genes that contribute to the risk of couples having a child with a genetic disorder are problem for short-read sequencing. Until now, laboratories have relied on multiple test technologies, including MLPA, Sanger sequencing, qPCR, long-range PCR, and others, to analyze the recommended genes. The AmplideX Nanopore Carrier Plus Kit addresses two problems for laboratories: it provides a single streamlined method, and it delivers comprehensive sequencing data compared to alternative assays. By combining novel AmplideX long-range PCR and nanopore long reads, it directly captures large genomic variants. The 11-gene panel includes the most prevalent recommended genes that cannot be detected accurately with legacy short-read sequencing methods, allowing labs to replace a patchwork testing approach with a single workflow to simplify sample-to-answer results. The kit also includes software to enable straightforward analysis without the need for advanced bioinformatics resources. Bio-Techne Corporation announced that Asuragen, a Bio-Techne brand, has teamed up with Oxford Nanopore Technologies to launch the AmplideX®? Nanopore Carrier Plus Kit, a new genetic panel and supporting analysis software for carrier screening research. This innovative kit helps laboratories resolve genes that are challenging to analyze by conventional short-read sequencing and only partially resolved by ancillary assays. The panel is available for research use only. In 2021, the American College of Medical Genetics and Genomics (ACMG) updated its recommendations for carrier screening to include many genes that cannot be analyzed by standard short-read sequencing. In fact, half of the 10 most common genes that contribute to the risk of couples having a child with a genetic disorder are problem for short-read sequencing. Until now, laboratories have relied on multiple test technologies, including MLPA, Sanger sequencing, qPCR, long-range PCR, and others, to analyze the recommended genes. The AmplideX Nanopore Carrier Plus Kit addresses two problems for laboratories: it provides a single streamlined method, and it delivers comprehensive sequencing data compared to alternative assays. By combining novel AmplideX long-range PCR and nanopore long reads, it directly captures large genomic variants. The 11-gene panel includes the most prevalent recommended genes that cannot be detected accurately with legacy short-read sequencing methods, allowing labs to replace a patchwork testing approach with a single workflow to simplify sample-to-answer results. The kit also includes software to enable straightforward analysis without the need for advanced bioinformatics resources.