Gateway Analytical Blog 2018 RDD Conference: Analysis of a Dry Powder Inhaler Active Pharmaceutical Ingredient Using Scanning Electron Microscopy

2018 RDD Conference: Analysis of a Dry Powder Inhaler Active Pharmaceutical Ingredient Using Scanning Electron Microscopy naylorb Mon, 05/07/2018 - 13:42Authors & ContributorsDavid ExlineAngela FlowersEmily LandspergerMay 07, 2018Automated SEM-EDS has been evaluated as a potential tool for determining the API particle size distribution (PSD) andmorphological characteristics, such as aspect ratio and roundness of particles, of a DPI. The only requirementfor this technique is an elemental distinction, such as the presence of an inorganic element in the API, in comparison to the excipients. In this instance, theautomated SEM-EDS technology has been applied to characterize a bromine- containing API in comparison to the carbon-rich lactose excipient of a DPI product.Download Resource