Cell Systems Blog Microfluidic Device from Primary Human Cells Sheds Light on Cancer Mechanism

3D models are often applauded for being more predictive than 2D cultures, but not all scientists know how to maximize their 3D models' biological relevance to reach their full potential.Using primary human cells (derived directly from human tissues) can greatly enhance the biological relevance of your models and steer your experiments in the right direction from the start.In a study by Kim et al., researchers use primary liver sinusoidal endothelial cells (Cat# ACBRI 566) to construct a 3D microfluidic human liver-chip to better understand how breast cancer-derived extracellular vehicles (EVs) can influence metastasis in the liver.More