Acuity: Acuity Spatial Genomics Announces Formation to Open up New Frontiers for in situ, Spatial 3D Genomics

Acuity Spatial Genomics, Inc. today announced the completion of a majority investment by Bruker Corporation (Nasdaq: BRKR). Acuity is a new venture focused on opening a new frontier in spatial 3D genomics and multiomic analyses for discovery. The novel technology platform of Acuity Spatial Genomics, enabled by an exclusive license to innovations from Harvard University, allows progress in genome-wide visualization of spatially resolved 3D chromatin architecture in individual cells and cell populations in situ. The company’s single-cell technology of OligoFISSEQ™ and accelerated super-resolution technology of OligoFISSEQ HD™ will make it possible for researchers to make a range of in situ discoveries—gaining insight into the 3D relationships between chromosomes, gene identities and their spatial position in the nucleus; physical gene positioning on chromosomes; chromosome 3D conformation; chromosome and gene copy number variation; chromosomal compartments, TADs and loops; and spatially resolved enhancer-promoter interactions. These unique spatially resolved genomic measurements and their relationships to information in the transcriptome and proteome provide critical context in understanding the complete multiomic picture.